As early as the 1990s, researchers in the field of bioinformatics began to try to use artificial intelligence technology to assist scientific research. In the era of big models, what role will big model technology play in the field of scientific research and discovery? The roundtable will explore the development of artificial intelligence-driven scientific research (AI4S), especially its application in fields such as bioinformatics. Discuss the potential role of big model technology in the field of scientific research and discovery, and how to promote scientific research efficiency and innovation. In-depth analysis of the integration of big model technology and scientific research discovery, as well as application cases in bioinformatics, materials science, drug discovery and other fields.